Have a plan
This event will cause many people harm both physically and economically for years to come. If you were directly involved in business that is ocean derived you are going to take a hit, sure down the road as lawsuits are filed and claims are paid you might recover but what about the right now?
This is a disaster for sure and it will be debated to death and then some but for the now lets look at bugging out. If that is your plan, you should have a general plan that can cover multiple disasters man made or natural.
Having our vehicle in tip top shape maintenance wise and a full tank of gas ( or close to it ) would give you a good step up. Do you have some supplies stashed in your vehicle? Maps, GPS, compass. One piece of equipment that I think everyone should have in their vehicle is some form of communications, one of the simplest, easiest and cheapest would be a CB radio. While on the road there is almost always information available on local conditions, knowing what is going on will help you plan your route, remember knowledge is power.